To run GUI-uploader, you need to install some additional packages. For Linux, run the line below to install the dependencies (in addition to Python 2.7): sudo apt-get install python-serial python-crcmod python-tkinter In Windows, install the following: https://www.python.org/ftp/python/2.7.10/python-2.7.10.msi https://pypi.python.org/packages/2.7/c/crcmod/crcmod-1.7.win32-py2.7.msi#md5=feba8cafe2849bc7bffadba6f21f37dd https://pypi.python.org/packages/any/p/pyserial/pyserial-2.7.win32.exe#md5=21555387937eeb79126cde25abee4b35